| 血小板白细胞聚集体与抗血小板治疗 |
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| 引用本文： | 王引明,刘春风. 血小板白细胞聚集体与抗血小板治疗[J]. 国际脑血管病杂志, 2005, 13(5): 348-351 |
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| 作者姓名： | 王引明 刘春风 |
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| 作者单位： | 215000,苏州大学附属第二医院神经内科;215000,苏州大学附属第二医院神经内科 |
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| 摘 要： | 在黏附分子的作用下,血小板和白细胞之间形成血小板白细胞聚集体(PLA)。PLA在动脉粥样硬化血栓形成性疾病的发生发展中有重要作用。临床研究发现,在此类疾病中PLA明显增加。不同的抗血小板药物对PLA形成的影响有所差异,监测PLA有助于指导抗血小板药的临床应用和筛选。
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| 关 键 词： | 血小板白细胞聚集体 动脉粥样硬化血栓形成性疾病 抗血小板药 |
| 修稿时间： | 2004-12-16 |
Platelet-Leukocyte Aggregate and Antiplatelet Therapy |
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| Yin-Ming Wang,Chun-Feng LIU. Platelet-Leukocyte Aggregate and Antiplatelet Therapy[J]. International Journal of Cerebrovascular Diseases, 2005, 13(5): 348-351 |
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| Authors: | Yin-Ming Wang Chun-Feng LIU |
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| Abstract: | The formation of platelet-leukocyte aggregate (PLA) was mediated by adhesion molecules. PLA formation plays an important role in both the development and progression of atherothrombotic diseases. Clinical studies have found that PLA formation was increased significantly in patients with such diseases. The PLA formation is affected variously by various antiplatelet agents. Monitoring of PLA formation is helpful in guiding the clinical use and selection of antiplatelet agents. |
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| Keywords: | platelet-leukocyte aggregate atherothrombotic disease antiplatelet agent |
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