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Emerging Human Metapneumovirus Gene Duplication Variants in Patients with Severe Acute Respiratory Infection,China, 2017–2019
Authors:Zhibo Xie  Jin Xu  Yunhui Ren  Aili Cui  Huiling Wang  Jinhua Song  Qiang Zhang  Manli Hu  Wenbo Xu  Yan Zhang
Institution:National Institute for Viral Disease Control and Prevention, Beijing, China (Z. Xie, A. Cui, H. Wang, J. Song, Q. Zhang, M. Hu, W. Xu, Y. Zhang);Henan Provincial Center for Disease Control and Prevention, Zhengzhou, China (J. Xu);Luohe Prefectural Center for Disease Control and Prevention, Luohe, China (Y. Ren)
Abstract:We detected human metapneumovirus (HMPV) in 72 (7.1%) of 1,021 patients hospitalized with severe acute respiratory infection in Luohe, China, during 2017–2019. We detected HMPV most frequently in young children and less often in adults. HMPV genotype A2c variants 111 nt and 180 nt duplications predominated, demonstrating their continuing geographic spread.
Keywords:acute respiratory tract infections  China  genetic variations  human metapneumovirus  Metapneumovirus  Pneumoviridae  severe acute respiratory infection  viruses  respiratory infection
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