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microRNA在胆囊癌中的作用
引用本文:成亚飞,王斌,王世明.microRNA在胆囊癌中的作用[J].临床肝胆病杂志,2020,36(8):1900-1904.
作者姓名:成亚飞  王斌  王世明
作者单位:山西医科大学研究生院,太原030001;山西医科大学第一医院肝胆胰外科,太原030001
摘    要:microRNA(miRNA)是一类广泛存在于真核生物体内的内源性非编码小分子RNA,成熟的miRNA由20~25个核苷酸序列组成。近些年随着研究者对miRNA研究的不断深入,发现其在胆囊癌的发生、发展、预后、化疗耐药以及早期诊断中具有重要作用。对miRNA在胆囊癌中作用的研究进展进行了综述。

关 键 词:胆囊肿瘤  微RNAS  诊断  治疗学

Role of microRNAs in gallbladder carcinoma
CHENG Yafei,WANG Bin,WANG Shiming.Role of microRNAs in gallbladder carcinoma[J].Chinese Journal of Clinical Hepatology,2020,36(8):1900-1904.
Authors:CHENG Yafei  WANG Bin  WANG Shiming
Institution:(Graduate school of Shanxi Medical University,Taiyuan 030001,China;Department of Hepatobiliary and Pancreatic Surgery,The First Hospital of Shanxi Medical University,Taiyuan 030001,China)
Abstract:MicroRNAs(miRNAs)are endogenous non-coding small molecular RNAs that widely exist in eukaryotes,and mature miRNAs are composed of 20-25 nucleotide sequences.With the deepening of the research on miRNAs in recent years,it has been found that miRNAs play an important role in the development,progression,prognosis,chemotherapy resistance,and early diagnosis of gallbladder carcinoma.This article reviews the research advances in the role of miRNAs in gallbladder carcinoma.
Keywords:gallbladder neoplasms  microRNAs  diagnosis  therapeutics
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