Isaacs综合征5例报告并文献回顾

目的探讨Isaacs综合征潜在的发病机制、临床表现、诊断及治疗。方法回顾性分析2017年3月至2019年3月收治的5例Isaacs综合征患者临床资料,并进行相关文献复习。结果 5例患者均为男性,主要表现为肌肉颤搐、痉挛、多汗,4例予以卡马西平和泼尼松口服治疗,效果良好。结论 Isaacs综合征临床罕见,对症治疗和免疫治疗不可或缺。

Cases report and literature review of Isaacs syndrome

Objective To explore the potential pathogenesis,clinical presentation,diagnosis and management of Isaacs syndrome.Methods The clinical data of five cases of Isaacs syndrome between March 2017 and March 2019 were analyzed retrospectively,and related literatures were reviewed.Results All five patients with Isaacs syndrome were males,and complained of muscle cramping,myokymia and hyperhidrosis.Four of them were treated with carbamazepine and prednisone,and got good responses.Conclusion Isaacs syndrome is a rare disorder in which symptomatic and immunomodulating therapy may play integral roles.