酒依赖脱瘾维持期患者复饮相关因素分析

目的:探讨酒依赖患者脱瘾维持期复饮的相关因素。方法:回顾分析在本院进行认知行为治疗(CBT)的188例酒依赖脱瘾维持期患者的临床资料,发现复饮酒113例(复饮酒组),未复饮酒75例(未复饮组)。将两组的临床资料进行对照分析,非条件二项Logistic回归分析复饮相关因素。结果:患者治疗后复饮率为60.1%。两组平均年龄、性别、饮酒年限、日均饮酒量、文化程度差异均无统计学意义(P>0.05)。两组婚姻状况不良、家族饮酒史阳性、酒精依赖严重程度问卷(SADQ-C)评分、Zung焦虑自评量表(SAS)评分、Zung抑郁自评量表(SDS)评分、人格障碍、肝脏异常、CBT例数差异均有统计学意义(P<0.05)。复饮与婚姻状况不良、家族饮酒史阳性、SADQ-C评分、SAS评分、SDS评分、人格障碍呈正相关,与肝脏异常、CBT治疗呈负相关(P均<0.01)。结论:婚姻状况不良、家族饮酒史阳性、SADQ-C高评分、焦虑、抑郁、人格障碍是酒依赖患者脱瘾维持期复饮危险因素,肝脏异常以及接受CBT治疗患者复饮率相对较低。

Analysis of the related factors of relapse in patients with maintenance period of alcohol dependence

Objective:To explore the related factors of relapse in alcohol dependent patients during the maintenance period.Method:The clinical data of 188 patients with alcohol dependence in the maintenance period of cognitive behavior therapy(CBT)in our hospital were analyzed retrospectively,with 113 cases of repeated drinking(relapse group)and 75 cases of not drinking again(no-relapse group).The clinical data of the two groups were analyzed,and the related factors of relapse were analyzed by unconditional binomial Logistic regression.Results:The rate of repeated drinking was 60.1%.There was no significant difference in age,gender,drinking years,daily drinking volume and education level between the two groups(all P>0.05).There were significant differences in poor marital status,family drinking history,the Severity of Alcohol Dependence Questionnaire(SADQ-C)score,Zung Self-rating Anxiety Scale(SAS)score,Zung Self-rating Depression Scale(SDS)score,personality disorders,liver abnormalities,CBT cases between the two groups(all P<0.05).Relapse was positively correlated with poor marital status,positive family drinking history,SADQ-C score,SAS score,SDS score and personality disorder,and negatively correlated with liver abnormality and CBT treatment(all P<0.01).Conclusion:Poor marital status,positive family drinking history,high SADQ-C score,anxiety,depression and personality disorder are the risk factors of relapse in alcohol dependent patients during the period of maintenance.Relapse rate in patients with liver abnormality and CBT treatment is relatively low.