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肝静脉压力梯度对肝硬化临床终点事件的预测
引用本文:何福亮,欧晓娟,王民,张冠华,王宇. 肝静脉压力梯度对肝硬化临床终点事件的预测[J]. 临床肝胆病杂志, 2020, 36(9): 1931-1935
作者姓名:何福亮  欧晓娟  王民  张冠华  王宇
作者单位:首都医科大学附属北京友谊医院肝病中心,北京100050
基金项目:北京市医管局中心青苗人才课题;北京市医院管理局消化内科学科协同发展中心消化专项特色项目;国家科技重大专项;技术推广;首都临床特色应用研究
摘    要:肝硬化是肝脏疾病的终末阶段,失代偿期肝硬化以门静脉高压为显著特征,目前肝静脉压力梯度是评估门静脉高压的“金标准”,具有重要的临床意义。对肝静脉压力梯度在代偿期及失代偿期临床终点事件中的预测作用以及在门静脉高压药物治疗效果评价中的应用进行阐述,以期为临床早预测、早预防、早干预门静脉高压提供依据。

关 键 词:肝硬化  高血压,门静脉  肝静脉压力梯度

Value of hepatic venous pressure gradient in predicting clinical end events in liver cirrhosis
HE Fuliang,OU Xiaojuan,WANG Min,ZHANG Guanhua,WANG Yu. Value of hepatic venous pressure gradient in predicting clinical end events in liver cirrhosis[J]. Chinese Journal of Clinical Hepatology, 2020, 36(9): 1931-1935
Authors:HE Fuliang  OU Xiaojuan  WANG Min  ZHANG Guanhua  WANG Yu
Affiliation:(Liver Research Center, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China)
Abstract:Liver cirrhosis is the end stage of liver disease,and decompensated liver cirrhosis has the significant feature of portal hypertension.At present,hepatic venous pressure gradient(HVPG)remains the“gold standard”for evaluating portal hypertension and thus has great significance in clinical practice.This article elaborates on the value of HVPG in predicting end events in compensated and decompensated liver cirrhosis and the application of HVPG in evaluating the therapeutic effect of drugs in the treatment of portal hypertension,so as to provide a basis for early prediction,early prevention,and early intervention of portal hypertension in clinical practice.
Keywords:liver cirrhosis  hypertension,portal  hepatic vein pressure gradient
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