| 中医药治疗非酒精性脂肪性肝病的重要靶位——肠道微生态 |
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| 引用本文： | 李红山,胡义扬.中医药治疗非酒精性脂肪性肝病的重要靶位——肠道微生态[J].临床肝胆病杂志,2020,36(1):14-18. |
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| 作者姓名： | 李红山 胡义扬 |
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| 作者单位： | 上海中医药大学肝病研究所,上海201203;中国科学院大学宁波华美医院,浙江宁波315010;宁波大学医学院,浙江宁波315211;上海中医药大学附属曙光医院临床研究中心,上海201203 |
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| 基金项目： | 国家自然科学基金重点项目(81830119);国家自然科学基金面上项目(81873109);上海市申康行动三年计划项目(16CR1019A) |
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| 摘 要： | 肠道微生态在非酒精性脂肪性肝病发病机制中具有重要意义。系统阐释非酒精性脂肪性肝病与肠道菌群、肠道菌代谢物和肠屏障功能关系,结合中医药调节肠道微生态与治疗非酒精性脂肪性肝病关系的研究概况,提出调节肠道微生态、维持肠道稳态是中医药治疗非酒精性脂肪性肝病的重要策略。
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| 关 键 词： | 非酒精性脂肪性肝病 中医学 胃肠道微生物组 |
Gut microecology: An important target of traditional Chinese medicine in the treatment of nonalcoholic fatty liver disease |
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| LI Hongshan,HU Yiyang.Gut microecology: An important target of traditional Chinese medicine in the treatment of nonalcoholic fatty liver disease[J].Chinese Journal of Clinical Hepatology,2020,36(1):14-18. |
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| Authors: | LI Hongshan HU Yiyang |
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| Institution: | (Institute of Liver Diseases,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China) |
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| Abstract: | Gut microecology plays an important role in the pathogenesis of nonalcoholic fatty liver disease. With reference to the research on traditional Chinese medicine in regulating gut microecology and treating nonalcoholic fatty liver disease,this article systematically elaborates on the association of nonalcoholic fatty liver disease with intestinal flora,gut bacterial metabolites,and gut barrier function and points out that the regulation of gut microecology and the maintenance of intestinal homeostasis are important measures for traditional Chinese medicine in the treatment of nonalcoholic fatty liver disease. |
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| Keywords: | non-alcoholic fatty liver disease TCM science gastrointestinal microbiome |
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