肝硬化门静脉血栓形成的危险因素

门静脉血栓(PVT)在肝硬化患者中较常见,合并PVT的静脉曲张更容易出血,止血失败率及再出血率更高,对于肝移植患者,其预后更差。目前PVT形成的相关危险因素较多,如肝功能严重程度、非选择性β受体阻滞剂的使用、门静脉血流速度等。重点对肝硬化PVT形成的危险因素进行综述,以进一步了解PVT形成的相关机制和PVT的危险程度。

Risk factors for the formation of portal vein thrombosis in patients with liver cirrhosis

Portal vein thrombosis(PVT) is commonly seen in patients with liver cirrhosis. Patients with varices complicated by portal vein thrombosis are more likely to experience bleeding,with higher failure rate of hemostasis and rebleeding rate,and the patients receiving liver transplantation may have a poorer prognosis. There are various risk factors for portal vein thrombosis,such as severity of liver dysfunction,use of non-selective beta blockers,and portal vein blood flow velocity. This article reviews the risk factors for portal vein thrombosis in patients with liver cirrhosis,in order to further understand the mechanism and risk level of portal vein thrombosis.