^131I治疗Graves’甲亢早发甲低的影响分析

目的综合分析Graves’甲亢^131I治疗后发生早发甲状腺功能减退（简称甲低）的相关影响因素。方法收集1183例Graves’甲亢行^131I治疗患者的一般资料、临床观察资料、实验室检查及甲状腺功能检查等资料，采用Logistic多元回归分析方法进行回顾性统计学分析。结果^131I治疗Graves’甲亢后早发甲低的相关因素中，病程、EHL、最高吸^131I率及TMA等因素量值是治疗后出现早发甲低的影响因素。结论由于影响Graves’甲亢^131I治疗后发生早发甲低这一并发症发生的因素较多，而且各因素间彼此相互作用，所以，从多角度、多因素进行综合考虑，利于个体化综合治疗方案的制定。

Influence analysis of iodine-131 therapy of graves' disease

Objective To make a comprehensive analysis of the related factors of early hypothy-roidism occurring in patients with graves＇ disease after iodine-131 treatment. Methods The information of iodine-131 treated graves＇ disease was collected including general data, clinical observation, laboratory data, thyroid function test, etc. Then a retrospective statistical analysis was carried out using logistic regression analysis. Results Among all the related factors of early hypothyroidism oeeurred after iodine-131 treated graves＇disease ,the disease course, thyroid uptake ratio of iodine-131, EHL and TMA titre are the more possible early hypothyroidiam occur. Conclusion Because of multiple factors＇influenees on iodine-131 curative effect and hypothroidism,we should comprehensively consider these influential factors from different aspects so as to individualize hterpaeutle plan.