超声引导下不同硬化剂注射治疗肝囊肿的疗效观察

目的探讨超声引导下不同硬化剂注射治疗肝囊肿的临床疗效。方法选取2011年2月～2013年2月收治的肝囊肿患者130例,按照随机数字表法分为观察组和对照组各65例。在B超导向下应用穿刺抽吸针抽出囊液,并注射硬化剂治疗,其中对照组硬化剂采用鱼肝油酸钠,注射量约为抽出囊液的25%,观察组硬化剂采用聚桂醇,在注入囊腔前反复冲入空气形成泡沫状,如囊肿直径约3cm囊肿注射5ml,直径为5cm注射10ml,均保留在囊内。随访并于手术后3个月、6个月、1年复查B超,术后1年评价疗效。结果观察组和对照组的治愈率分别为（65.28%VS 63.24%）,总有效率分别为（97.22%VS 94.12%）,两组比较差异无统计学意义（P＞0.05）;观察组和对照组术后3个月、6个月、1年囊肿体积均较术前明显减小,差异有统计学意义（P〈0.05）,两组术前及术后3个月、术后6个月、术后1年囊肿体积比较差异无统计学意义（P＞0.05）;观察组在术后疼痛、腹胀、呕吐发生率方面明显低于对照组,差异有统计学意义（P〈0.05）。结论采用聚桂醇作为硬化剂超声引导下穿刺肝囊肿硬化治疗的临床疗效与鱼肝油酸钠相当,但其不良反应少,值得临床推广应用。

Curative effect of injection of different hardeners in the treatment of hepatic cyst under the guidance of ultrasound

Objective To investigate the curative effect of injection of different hardeners in the treatment ot hepatm cyst under the guidance of ultrasound.Methods 130 cases with liver cyst admitted to the hospital from Feb, 2011 to Feb,2013 were divided into the observation group and the control group with 65 cases in each group according to the random number.Needle aspiration was used to withdraw cyst fluid under the guidance of ultrasound. And all patients were treated with injection of hardener.The control group were given sodium morrhuate as hardener with the injection content as 25 % of the withdrawing cyst fluid.The observation group,however, were given lauromacrogol as hardener, and cyst cavity was repeatedly filled with air to creat spumescence. Then if the diameter of cyst was 3 cm, 5 ml of lauromacrogol was iniected into and kept in the cyst;if the diameter of cyst was 5 cm,5 ml of lauromacrogol was injected into and kept in the cyst.All the cases were given follow-up visits and rechecked by B-ultrasound 3 months,6 months and one year later.Their curative effect was evaluated after a year.Results The cure rates of the observation group and the control group were 65.28% and 63.24%, respectively. Their total effective rates were 97.22% and 94.12%, respectively.There was no significant statistical difference between two groups in these aspects（ P 〉0.05）.3 months,6 months and 1 year later,the cyst volume of both the observation group and the control group after surgery were significantly smaller than those before surgery, so the difference was statistically significant（ P 〈0.05）.There was no statistical significance in the comparison of cyst volumes between two groups before surgery and 3 months, 6 months and 1 year after surgery （ P 〉0.05）.The incidence of postoperative pain, of abdominal distention and of vomitting of the observation group were significantly lower than those of the control group,so the difference was statistically significant（ P 〈0.05）.Conelusion Using lauromacrogol as