肿瘤大小与早期胃癌预后的关系

目的 探讨早期胃癌的预后因素,特别是肿瘤大小与早期胃癌预后的关系.方法 回顾性分析1998年1月至2002年2月119例在中国医学科学院肿瘤医院外科治疗的早期胃癌的临床病理特征,分析早期胃癌的预后因素.结果 本组早期胃癌病例5年生存率为90.9%,其预后主要与肿瘤大小相关,直径＜2 cm组、2 cm≤直径＜4 cm组与直径≥4 cm组5年生存率分别为100%、92.0%、80.8%,差异有统计学意义,P=0.024.同时比较淋巴结转移及浸润深度等因素,P值分别为0.816及0.371,差异无统计学意义.肿瘤大小与其他预后因素之间无明显相关性.结论 早期胃癌浸润深度及淋巴结转移与其预后关系不明确,而肿瘤大小很可能是早期胃癌独立的预后因素,对指导早期胃癌预后及手术选择有实用价值.

Tumor size and prognosis in patients with early gastric carcinoma

Objective To investigate the prognostic factors of EGC patients,especially the relationship between prognosis and tumor size.Methods Clinical data of 119 EGC cases from 1998 to 2002 were analyzed retrospectively.Results The overall 5-year survival rate was 90.9%.and the survival rate of patients with tumor D＜2 cm.2 cm≤D＜4 cm and D≥4 cm respectively was 100%,92.0%and 80.8%(P=0.024).In this group,tumor stage,lymph node metastasis and tumor invasion depth did not affect the survival statistically.There was no correlation between tumor size and other prognostic factors.Conclusion Tumor size is an independent prognostic factor of patients with EGC,which may have some relevance to the surgical approach of EGC.