| 泽兰两个化学部位对凝血功能的影响 |
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| 引用本文： | 田泽,高南南,李玲玲,余竞光,罗秀珍.泽兰两个化学部位对凝血功能的影响[J].中药材,2001,24(7):507-508. |
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| 作者姓名： | 田泽 高南南 李玲玲 余竞光 罗秀珍 |
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| 作者单位： | 中国医学科学院协和医科大学药用植物研究所, |
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| 摘 要： | 目的:寻找确定泽兰活血化瘀有效部位。方法:比浊法测定体内外血小板聚集;剪尾法和玻管法测定出血时间和凝血时间。结果:泽兰的两个化学部位F04-A、F04-B均可以抑制大鼠体外血小板聚集和小鼠体内血小板聚集,延长小鼠凝血时间,但对出血时间无明显影响。结论:泽兰的两个化学部位F04-A、F04-B均具有抗凝血和抑制血小板聚集的作用,且F04-A的作用可能强于F04-B,是泽兰活血化瘀的有效部位。
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| 关 键 词： | 泽兰 血小板聚集 凝血 出血 |
| 修稿时间： | 2000年12月20 |
Effect of Two Extracted Fraction from Lycopus lucidus on Coagulation Function |
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| Tian Ze,Gao Nannan,Li Lingling,Yu Jingguang,Luo Xiuzhen.Effect of Two Extracted Fraction from Lycopus lucidus on Coagulation Function[J].Jorunal of Chinese Medicinal Materials,2001,24(7):507-508. |
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| Authors: | Tian Ze Gao Nannan Li Lingling Yu Jingguang Luo Xiuzhen |
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| Institution: | Institute of Medicinal Plant, Chinese Academy of Medical Sciences, Beijing 100094. |
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| Abstract: | Objective: To find and define the effective fraction of Lycopus lucidus on coagulation. Methods: Method of comparing turbidity, method of cutting a part of the mice tail and method of breaking glass tube. Results:The two extracted fraction from lycopus lucidus F04-0A and F04-B could inhibit rats platlet aggregation in vitro and mice platelet aggregation in vivo.They could also prolong mice blood coagulation time. However, they had no effect on bleeding time. Conclusion:Both F04-A and F04-B had effects on inhibiting platelet aggregation and blood coagulation.Morever,the activity of F04-A was probably stronger than that of F04-B.F04-A maybe the effective fraction from Lycopus lucidus on promoting blood circulation and removing blood stasis. |
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| Keywords: | Lycopus lucydus Platelet aggregation Blood coaguladon Bleeding |
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