| 内皮素对心肌缺血／再灌注性心律失常的影响 |
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| 引用本文： | 郑华光 余霞君. 内皮素对心肌缺血／再灌注性心律失常的影响[J]. 军医进修学院学报, 1994, 15(1): 8-11 |
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| 作者姓名： | 郑华光 余霞君 |
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| 摘 要： | 本文从离体大鼠心脏和缺血性心脏停搏患者两方面观察了ＥＴ对心肌缺血／再灌注性心律失常的影响。心肌缺血／再灌注后组织的ＥＴ含量增加。外源性ＥＴ可加重心肌缺血／再灌注损伤和心律失常。异搏定、巯甲丙脯酸和ＥＴ抗血清有部分改善ＥＴ引起的心肌损伤和心律失常的作用。人心脏手术缺血性停搏后血浆ＢＴ水平进行性增加，但不是心律失常发生的主要因素。
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| 关 键 词： | 内皮素 心律失常 心肌缺血 再灌注 |
Effect of Endothelin on Ischemia/Reperfusion Induced Arrhythmia |
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| Zheng Huaguang.Yu Xiajun. Effect of Endothelin on Ischemia/Reperfusion Induced Arrhythmia[J]. Academic Journal of Pla Postgraduate Medical School, 1994, 15(1): 8-11 |
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| Authors: | Zheng Huaguang.Yu Xiajun |
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| Affiliation: | Department of Cardiology |
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| Abstract: | effect of endothelin(ET) on ichemia/reperfusion (I/R)induced arrhythmia was studied in isolated ret heart and patients with cardiac ischemic arrest.ET in myocardial ti-ssue of ret increased during I/R.ET may aggravate I/R injury and arrhythmia.Verapamil, captopril and ET antibody may partialy improve ischemic myocardial injury and arrhythmia caused by ET.Blood plasma ET level of patients increased during cardiac ischemic arrest. However,ET was not associated with arrhythmia induced by ischemic arrest. |
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| Keywords: | Endothelins Arrhythmia Myocardial ischemia Reperfusion |
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