| 鲜红斑痣的发病机制研究进展 |
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| 引用本文： | 刘莲,张自晖,郝丹,梅蓉,李二龙,孙本森,蒋献. 鲜红斑痣的发病机制研究进展[J]. 中国麻风皮肤病杂志, 2019, 35(4): 253-256. DOI: 10.12144/zgmfskin201904253 |
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| 作者姓名： | 刘莲 张自晖 郝丹 梅蓉 李二龙 孙本森 蒋献 |
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| 作者单位： | 四川大学华西医院皮肤科，四川成都，610041 |
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| 摘 要： | 鲜红斑痣(port-wine stains,PWS)是一种主要发生于皮肤及黏膜的血管疾病,在新生儿中的发病率约为0.3%~0.5%。PWS的发病机制目前尚不清楚,可能与体细胞基因突变、血管神经比例异常、遗传等因素相关,本文将对PWS的发病机制进行综述。
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| 关 键 词： | 鲜红斑痣 血管畸形 发病机制 基因突变 遗传 |
Advances in the Pathogenesis of Port Wine Stains |
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| LIU Lian,ZHANG Zihui,HAO Dan,MEI Rong,LI Erlong,SUN Bensen,JIANG Xian. Advances in the Pathogenesis of Port Wine Stains[J]. China Journal of Leprosy and Skin Diseases, 2019, 35(4): 253-256. DOI: 10.12144/zgmfskin201904253 |
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| Authors: | LIU Lian ZHANG Zihui HAO Dan MEI Rong LI Erlong SUN Bensen JIANG Xian |
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| Affiliation: | Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu 610041, China |
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| Abstract: | Port wine stains (PWS) is a kind of vascular disease mainly affecting the skin and mucous membrane. The incidence of PWS in the newborn is about 0.3%~0.5%.The pathogenesis of PWS is unkown and may be concerned with somatic gene mutation, abnormal proportion of vessels and nerves, heredity, etc. The pathogenesis of PWS is reviewed in this paper. |
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| Keywords: | port-wine stains vascular malformation pathogenesis gene mutation heredity |
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