深圳市男男性接触人群梅毒合并HIV感染状况及其危险因素分析

目的：了解深圳市近6个月内发生过同性临时性行为的MSM人群梅毒合并HIV感染状况及其相关影响因素。方法：运用滚雪球法和同伴推动抽样法招募MSM进行问卷调查和血清学检测，采用χ2检验和Logistic回归分析梅毒HIV合并感染的相关影响因素。结果：共调查434例MSM，梅毒和HIV感染率分别为16.4%和12.2%，梅毒合并HIV感染率为7.3%。年龄越大（OR=4.0，P=0.0007）、高中/中专文化者（OR=6.5，P=0.0081）、性角色以被动方为主者（OR=12.1，P=0.0017）、多个同性肛交性伴者（OR=1.5，P=0.0455）、不能坚持每次使用安全套者（OR=2.9，P=0.0236），其梅毒合并HIV感染风险越高。结论：需要采取更大努力来应对该人群的梅毒和HIV双重感染问题。

Co-infection of syphilis and HIV and risk factors among men who have sex with men in Shenzhen

Objective: To understand the co-infection of syphilis and human immunodeficiency virus (HIV) and the risk factors among men who have sex with men (MSM) (who had temporary anal sex in the last 6 months) in Shenzhen. Methods: The samples were collected by snowball and respondent-driven sampling method. Chi-square test and multivariate logistic regression model were used to analyze the factors associated with co-infection of syphilis and HIV. Results: A total of 434 MSM were investigated. The infection rates of syphilis, HIV and co-infection of syphilis-HIV were 16.4%, 12.2%, and 7.3%, respectively. Multivariate logistic regression analysis showed that the older MSM (OR=4.0, P=0.0007), senior middle school level (OR=6.5, P=0.0081), playing exclusively receptive roles in anal sexual intercourse (OR=12.1, P=0.0017), having more anal sexual partners (OR=1.5, P=0.0455) and not always using condom in anal sexual intercourse in the past 6 months (OR=2.9, P=0.0236) were associated risk factors for syphilis and HIV co-infection. Conclusion: More efforts are needed to deal with the high co-infection of syilhilis and HIV in this population.