| 中西医结合治疗冠心病患者临床疗效观察 |
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| 引用本文： | 于长生,宫丽鸿,赵殿臣.中西医结合治疗冠心病患者临床疗效观察[J].辽宁中医药大学学报,2019(5):98-101. |
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| 作者姓名： | 于长生 宫丽鸿 赵殿臣 |
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| 作者单位： | 辽宁中医药大学附属医院 |
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| 基金项目： | 国家中医药管理局国家中医临床研究基地业务建设科研专项课题项目(JDZΧ2015033) |
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| 摘 要： | 目的:观察体外反搏联合中西医结合治疗冠心病患者的临床疗效及对血清MCP-1的影响,探求体外反搏联合中西医结合治疗冠心病患者的疗效机制。方法:就诊于我院的冠心病(不稳定型心绞痛)患者,从中选取120例痰瘀互结证患者,采用随机对照原则,将其分为治疗组及对照组,60例/组。对照组给予抗血小板、他汀及硝酸酯类等西药常规治疗,同时配合稳斑汤治疗;治疗组在对照组用药基础上加用EECP治疗,治疗前后记录各组患者的中医证候积分、中医证候疗效、心绞痛症状积分、心绞痛症状疗效、单核细胞趋化蛋白-1(MCP-1),并进行比较分析。结果:疗程结束后,与治疗前相比,治疗组和对照组中医证候积分及心绞痛症状积分均有效降低(P<0.05);血清MCP-1含量均显著降低(P<0.05);治疗组中医证候积分、心绞痛症状积分降幅优于对照组,且中医证候疗效、心绞痛症状疗效优于对照组(P<0.05),血清MCP-1含量显著低于对照组(P<0.05)。结论:稳斑汤配合西药治疗联合体外反博能有效治疗痰瘀互结证冠心病(不稳定型心绞痛)患者,其治疗机制可能与MCP-1表达水平的降低有关。
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| 关 键 词： | 中西医结合 体外反搏 冠心病 单核细胞趋化蛋白-1 |
Clinical Effects of Integrated Traditional Chinese and Western Medicine on Patients with Coronary Atherosclerotic Heart Disease and the Impact on Serum MCP-1 |
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| YU Changsheng,GONG Lihong,ZHAO Dianchen.Clinical Effects of Integrated Traditional Chinese and Western Medicine on Patients with Coronary Atherosclerotic Heart Disease and the Impact on Serum MCP-1[J].Journal of Liaoning University of Traditional Chinese Medicine,2019(5):98-101. |
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| Authors: | YU Changsheng GONG Lihong ZHAO Dianchen |
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| Institution: | (Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110032,Liaoning,China) |
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| Abstract: | YU Changsheng;GONG Lihong;ZHAO Dianchen(Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110032,Liaoning,China) |
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| Keywords: | integrated traditional Chinese and Western medicine external counterpulsation coronary heart disease MCP-1 |
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