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中药对肝癌细胞信号转导通路影响的研究进展
引用本文:濮忠建,华海清. 中药对肝癌细胞信号转导通路影响的研究进展[J]. 中国中药杂志, 2011, 36(7): 951-954
作者姓名:濮忠建  华海清
作者单位:1. 南京中医药大学,江苏,南京,210029
2. 解放军第八一医院,全军肿瘤中心内科,江苏,南京,210002
基金项目:全军"十一五"中医药重大临床攻关基金项目(2006051005)
摘    要:随着对肿瘤信号转导通路研究的不断深入,人们对肿瘤细胞内部复杂的信号转导机制以及它们对肿瘤生长、凋亡和转移等的影响越来越了解.目前,中药及其提取物通过作用于信号转导通路诱导肝癌细胞凋亡、影响肝癌血管生成的研究已取得可喜进步.现对近年来有关文献进行回顾,就此进展作一综述.

关 键 词:中药  肝癌细胞  信号转导通路
收稿时间:2010-10-18

Advances in research on Chinese medicines that can induce apoptosis of hepatocellular carcinoma cells by the signal transduction pathway
PU Zhongjian and HUA Haiqing. Advances in research on Chinese medicines that can induce apoptosis of hepatocellular carcinoma cells by the signal transduction pathway[J]. China Journal of Chinese Materia Medica, 2011, 36(7): 951-954
Authors:PU Zhongjian and HUA Haiqing
Affiliation:Nanjing University of Chinese Medicine, Nanjing 210029, China;Department or Oncology, Cancer Center of PLA,81 Hospital of PLA, Nanjing 210002, China
Abstract:As the research on the signal transduction pathway of tumor is developing, people has become more aware of the confusion of the signal transduction mechanisms on the tumor cells and their effects on tumor growth, apoptosis, and metastasis. Currently, the research that Chinese medicine and its extract inducing apoptosis and angiogenesis of hepatocellular carcinoma by acting on the signal transduction pathway has made gratifying progress. In this article, we will provide an overview of recent literature about this.
Keywords:Chinese medicines   hepatocellular carcinoma cells   signal transduction pathways doi:10.4268/cjcmm20110727
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