Treatment of polymorphic light eruption |
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Authors: | Ling Tsui C Gibbs Neil K Rhodes Lesley E |
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Affiliation: | Photobiology Unit, Dermatology Centre, University of Manchester, Hope Hospital, Manchester, UK. |
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Abstract: | Polymorphic light eruption (PLE) is a highly prevalent photosensitivity disorder, estimated to affect 11-21% people in temperate countries. Typically, PLE appears as a recurrent pruritic eruption comprising papules and/or vesicles and/or plaques, which occurs on photo-exposed skin sites following sun exposure, and which heals without scarring. Commoner in females, the aetiology is uncertain, although there is evidence of an immune basis. We perform a review of the prophylaxis and treatment of this condition. While sun protection, corticosteroids and desensitization phototherapy are the mainstays of management, a range of anti-inflammatory and immunomodulatory agents are reported. |
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Keywords: | Polymorphic light eruption review treatment |
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