原发性高血压患者内脏脂肪分布与左心室肥厚的相关性

目的通过观察原发性高血压患者腹部CT内脏脂肪/皮下脂肪比值(V/S)及体质量指数(BMI)、腰臀比(WHR)、腰围/身高比值(WHtR )与原发性高血压左心室肥厚（LVH）的关系，探讨原发性高血压患者腹部CT内脏脂肪分布与LVH的相关性。方法对80例入选者行上腹CT检查及心脏超声检查，分别测量上腹CT的V/S及心脏超声左心室质量指数（LVMI），并记录年龄、收缩压、舒张压、BMI、WHR和WHtR，应用统计学方法观察各参数与LVMI的关系。结果原发性高血压患者LVH组与非LVH组年龄、收缩压和舒张压差异均无统计学意义（P＞0.05），而原发性高血压患者LVH组V/S、BMI、WHR和WHtR显著高于非LVH组（P＜0.05）；V/S、WHtR、WHR和BMI与LVMI之间有线性回归关系，且V/S回归系数最大。结论肥胖对原发性高血压患者LVH有促进作用，内脏脂肪聚集与LVH关系尤为密切。

Relationship between left ventricular hypertrophy and visceral adipose tissue distribution

ObjectiveTo investigate the relationship between left ventricular hypertrophy (LVH) and visceral adipose tissue distribution in patients with essential hypertension (EH). MethodsAge， gender， blood pressure， heights， body mass， waist circumference and hip circumference were recorded in 80 patients with EH. Cardiac ultrasound examination and abdominal CT were performed， then V/S and LVMI were calculated. ResultsThere were no significant difference in age， systolic pressure， and diastolic pressure between LVH group and non LVH group (P>0.05). The V/S， BMI， WHR and WHtR were significantly higher in LVH group than in non LVH group (P<0.05). And there were linear regression between V/S， WHtR， WHR， BMI and LVMI. ConclusionObesity contributes to the LVH in EH patients， and visceral adipose tissue plays significant role in the pathogenesis of LVH．