| 免疫抑制剂在炎症性肠病治疗中的应用进展 |
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| 引用本文： | 李玥,钱家鸣.免疫抑制剂在炎症性肠病治疗中的应用进展[J].临床荟萃,2016,31(8):824. |
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| 作者姓名： | 李玥 钱家鸣 |
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| 作者单位： | 中国医学科学院北京协和医学院 北京协和医院消化科，北京 100730 |
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| 摘 要： | 炎症性肠病包括溃疡性结肠炎和克罗恩病，是病因尚不十分明确的肠道慢性反复的非特异性炎症。免疫抑制剂是重要的药物治疗方法，维持无激素长期缓解，主要用于克罗恩病和激素依赖或抵抗的溃疡性结肠炎的维持治疗。常用的免疫抑制剂包括硫嘌呤类、甲氨蝶呤、环孢素等药物。
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| 关 键 词： | 炎性肠疾病 免疫抑制剂 硫唑嘌呤 甲氨蝶呤 环孢素 |
Recent advances of immunosuppressive therapy in inflammatory bowel disease |
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| Li Yue,Qian Jiaming.Recent advances of immunosuppressive therapy in inflammatory bowel disease[J].Clinical Focus,2016,31(8):824. |
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| Authors: | Li Yue Qian Jiaming |
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| Institution: | Department of Gastroenterology， Peking Union Medical College Hospital， Beijing 100730， China; |
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| Abstract: | Inflammatory bowel disease comprises ulcerative colitis and Crohn disease， both of which are characterized by a tendency of chronic or relapsing immune activation and inflammation within the gastrointestinal tract. Immunomodulating drugs， including azathioprine， methotrexate and cyclosporine etc. are most useful in managing steroids resistant or dependent patients to achieve steroids free remission. |
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| Keywords: | inflammatory bowel diseases immunosuppressive agents azathioprine methotrexate cyclosporine |
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