甘肃定西地区血脂异常流行病学调查及危险因素分析

目的调查甘肃定西地区血脂异常流行状况，分析其主要危险因素，为临床有效干预提供依据。方法采用分层整群随机抽样的方法，抽取甘肃定西地区20~74岁5年以上的常住人口1 702例，并发放问卷调查、体格检查及生化检查。采用中国成人血脂异常防治指南诊断标准，评估甘肃定西地区受检人口血脂异常检出率，并分析其影响因素。结果甘肃定西地区血脂异常的总体患病率为37.0%，其中男性44.1%，女性30.8%，男性患病率高于女性（χ2=27.86，P=0.00）。高甘油三酯、高总胆固醇、低高密度脂蛋白胆固醇、高低密度脂蛋白胆固醇患病率分别为23.0%、4.0%、16.5%和4.5%。性别和肥胖程度是血脂异常的危险因素。结论甘肃定西地区血脂异常患病率较高，男性患病率高于女性，性别、肥胖程度是其主要危险因素。

Dyslipidemia epidemiological survey and risk factors analysis in Gansu Dingxi

ObjectiveTo investigate the prevalence of dyslipidemia in population aged 20 to 74 years in Dingxi，and analyze the risk factors in a basis for clinical intervention. MethodsA total of 1 702 participants 20 to 74 years old living in the local residence for at least 5 years were selected using a stratified cluster and random sampling design. All subjects completed a questionnaires survey，immediately following a physical examination and laboratory test. The prevalence of dyslipidemia was assessed according to diagnostic criteria，namely Chinese adult dyslipidemia prevention guideline，and the risk factors were analyzed. ResultsThe overall prevalence of dyslipidemia in Dingxi was 37.0%，the prevalence in men was higher than that in women(44.1% vs 30.8%，χ2=27.86，P=0.00). The prevalence of elevated triglycerides，elevated total cholesterol，elevated low density lipoprotein and low high density lipoprotein cholesterol were 23.0%，4.0%，16.5% and 4.5%， respectively. Gender and obesity were the risk factors for dyslipidemia. ConclusionThe prevalence of dyslipidemia in Dingxi is high，especially in men. Gender and obesity are the main risk factors for dyslipidemia.