老年吸入性肺炎临床特征荟萃分析

目的 分析老年吸入性肺炎的临床表现及病原学特点,为经验性治疗提供参考。方法 在中国期刊全文数据库检索2000~2014年有关老年吸入性肺炎的相关文章,从中筛选出资料完整,统计确切的文献36篇,进行分析总结。结果 2 851例老年吸入性肺炎患者的临床表现多不典型,均伴有慢性基础疾病,中枢神经系统疾病最多。主要病原菌是革兰阴性菌,且耐药率较高。结论 应当提高对老年吸入性肺炎临床表现的认识和早期诊断率,合理有效的经验性抗感染治疗,降低病死率。

Clinical features in aged patients with aspiration pneumonia: a meta-analysis

Objective To analyze the clinical and etiologic features in elderly patients with aspiration pneumonia and to provide a fundamentism for empirical therapy.Methods A total of 36 literatures with complete and precise data about aged patients with aspiration pneumonia were searched in CNKI database from 2000 to 2014, then analyzed and summarized.Results All 2 851 cases of aspiration pneumonia in aged patients had atypical clinical signs and symptoms,and the patients all associated with a variety of underlying diseases, especially with the central nervous system diseases. The main infectious pathogens were gram-negative bacteria with high resistant rate.Conclusion Understanding of clinical features and early diagnostic rate in aged patients with aspiration pneumonia should be elevated, reasonable and effective empirical anti-infection treatment should be performed to reduce the mortality.