| 黄曲霉毒素B1诱发大鼠肝癌及硒心癌机理的研究 |
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| 引用本文： | 王洛权 朱昌仁. 黄曲霉毒素B1诱发大鼠肝癌及硒心癌机理的研究[J]. 中华预防医学杂志, 1989, 23(5): 289-292 |
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| 作者姓名： | 王洛权 朱昌仁 |
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| 摘 要： |
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| 关 键 词： | 肝癌 黄曲霉毒素B1 硒 鼠 |
The study of aflatoxin B1-induced hepatocarcinogenesis of rats and mechanism of selenium''s inhibitory effect on carcinogenesis |
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| L Q Wang. The study of aflatoxin B1-induced hepatocarcinogenesis of rats and mechanism of selenium''s inhibitory effect on carcinogenesis[J]. Chinese Journal of Preventive Medicine, 1989, 23(5): 289-292 |
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| Authors: | L Q Wang |
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| Abstract: | Liver cancers of rats were induced by aflatoxin B1. Two other groups were given 3 ppm and 6 ppm selenium in water. It was found that Selenium had distinct inhibitory effect on carcinogenesis. 61% of rats not given selenium came down with liver carcinoma, whereas those given selenium no carcinogenetic changes were found. In the early stage selenium inhibited the formation of liver hyperplastic foci, in the late stage its effect was on the carcinogenetic change of the hyperplastic foci. |
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