| 正交设计法研究补肾通痹颗粒提取工艺 |
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| 引用本文： | 周素娟.正交设计法研究补肾通痹颗粒提取工艺[J].中华中医药学刊,2007,25(3):606-607. |
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| 作者姓名： | 周素娟 |
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| 作者单位： | 石家庄市中医院,河北,石家庄,050051 |
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| 摘 要： | 目的：优选补肾通痹颗粒提取工艺。方法：采用正交设计法，以槲皮素、原儿茶醛薄层斑点，延胡索乙素含量为指标，优选提取工艺。结果：最优提取工艺为中等粒度的醋延胡索，50％的乙醇，8倍溶剂量，提取2次，高温减压浓缩。结论：正交设计法试验优选的补肾通痹颗粒提取工艺条件稳定、可行。
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| 关 键 词： | 补肾通痹颗粒 提取工艺 正交设计法 |
| 文章编号： | 1673-7717（2007）03-0606-02 |
| 收稿时间： | 2006-10-14 |
| 修稿时间： | 2006-10-14 |
Study on Extraction Process of Bushen Tongbi Granuls with Orthogonal Design Method |
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| ZHOU Su-juan.Study on Extraction Process of Bushen Tongbi Granuls with Orthogonal Design Method[J].Chinese Archives of Traditional Chinese Medicine,2007,25(3):606-607. |
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| Authors: | ZHOU Su-juan |
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| Institution: | Shijiazhuang Hospital of TCM, Shijiazhuang 050051, Hebei, China |
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| Abstract: | Objective:To optimize the extraction process of Bushen Tongbi Granuls.Methods: Using orthogonal design method,to apply extract yield of Rhizoma Coptis and the extract amount of berberine hydrochloride as observing indexes,to measure the content of dl-tetrahydropalmatine with HPLC.Results:The optimum extraction process was as follows,adding 8 times of 50%alcohol into coptis meal,refluxing and extracting for 2 times,one hour every time.Conclusion: This optimized process is simple,stable and efficient. |
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| Keywords: | bushen Tongbi granuls extraction process orthogonal design |
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