| HFRS患者尿抗体检测的意义 |
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| 引用本文： | 肖书渊,朱宝莲,张美英,J.Meegan,郑志明,向近敏. HFRS患者尿抗体检测的意义[J]. 武汉大学学报(医学版), 1988, 0(2) |
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| 作者姓名： | 肖书渊 朱宝莲 张美英 J.Meegan 郑志明 向近敏 |
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| 作者单位： | 湖北医学院病毒研究所，湖北医学院病毒研究所，湖北医学院病毒研究所，United States Army Medical Research Institute of Infectious Diseases，湖北医学院病毒研究所，湖北医学院病毒研究所 |
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| 摘 要： | 应用二种ELISA技术分别对25名HFRS患者203份尿液标本特异性IgG、IgM抗体进行了动态研究,发现其抗体阳性率分别为84％(21/25)与60％(15/25),而16％(4/25)的患者既无IgG又无IgM抗体,表明尿抗体检测阴性不能排除HFRS,而只能作为参考指标。病程中IgG抗体平均滴度与每日标本的阳性率均高于IgM,证实了尿中抗体的出现是由于肾脏受损而漏出的结论。
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| 关 键 词： | 出血热,流行性/诊断 肾/病理学 免疫球蛋白M类/尿 免疫球蛋白G类/尿 |
Significations of Dètecting the Urine Antibodies of the patients With HFRS |
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| Xiao Shuyuan,et al. Significations of Dètecting the Urine Antibodies of the patients With HFRS[J]. Medical Journal of Wuhan University, 1988, 0(2) |
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| Authors: | Xiao Shuyuan et al |
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| Abstract: | A sequential study, on the specific IgG and IgM antibodies in 203 urine specimens from 25 HFRS patients was made with two kinds of ELISA techniques. The positive rates of IgG and IgM were 84% (21/25) and 60% (15/25) respectively, and 16% of the patients excreted neither of them, which indicates that the negative results of these detections can't be used to exclude the diagnosis of HFRS. It is also found that the each-day samples' positive rates and mean titer of IgG are higher than those of IgM in the whole course of illness, proving that they are leakages from the damaged kidneys. |
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| Keywords: | hemorrhagic fever epidemic/DI kidney/PA IgM/UR IgG/UR |
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