| 人工肝在肝移植围手术期的应用 |
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| 引用本文： | 邢同海,彭志海,裘国强,刘育健,赵守业. 人工肝在肝移植围手术期的应用[J]. 肝脏, 2003, 8(4): 9-12 |
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| 作者姓名： | 邢同海 彭志海 裘国强 刘育健 赵守业 |
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| 作者单位： | 200080,上海市第一人民医院普外科 |
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| 基金项目： | 上海市科技发展基金项目 (编号024119002)，上海市科委专项基金资助 (编号QY0401018) |
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| 摘 要： | 目的 探讨人工肝支持系统在肝移植围手术期的应用效果。方法采用非生物人工肝治疗9例等待供肝患者，3例肝移植术后患者(包括1例等待供肝成功过渡到肝移植患者)。9例等待供肝患者中4例成功过渡到肝移植。结果 人工肝支持后患者肝性脑病有所好转，血清胆红素明显下降。4例成功过渡到肝移植的启者中2例痊愈出院，已存活12和14个月。结论 术前使用人工肝支持系统能改善患者一般情况；原位肝移植加人工肝支持系统是治疗慢性肝衰竭的有效方法。
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| 关 键 词： | 肝移植 围手术期 人工肝支持系统 持续性血液净化疗法 血浆置换 |
Perioperative application of artificial liver support system in orthotopic liver transplantation |
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| XING Tonghai,PENG Zhihai,QIU Guoqiang,et al.. Perioperative application of artificial liver support system in orthotopic liver transplantation[J]. Chinese Hepatology, 2003, 8(4): 9-12 |
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| Authors: | XING Tonghai PENG Zhihai QIU Guoqiang et al. |
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| Affiliation: | XING Tonghai,PENG Zhihai,QIU Guoqiang,et al. General Surgery Department,Shanghai No.1 People's Hospital Affiliated to Shanghai Jiaotong University,Shanghai 200080 |
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| Abstract: | Objective To investigate the applicable artificial liver support system (ALSS) during the perioperative orthotopic liver transplantation (OLT).Methods We used ALSS to treat 9 patients waiting for liver donor and one patient received OLT. 4 patients successfully underwent OLT.Results Improvement in hepatic encephalopathy and reduction in serum bilirubin were achieved in all cases after ALSS. 2 patients had excellent quality of life for 12 and 14 months after OLT.Conclusion ALSS can improve the general condition of the patients before operation. OLT plus ALSS is one of the most effective therapies for chronic hepatic failure patients. |
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| Keywords: | Liver transplantation Artificial Liver Liver failure |
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