原发性十二指肠癌43例临床分析

目的:探讨原发性十二指肠癌的临床特点、诊断、治疗方法,为早期诊治提供依据.方法:回顾性总结分析43例原发性十二指肠癌的临床资料.结果:43例原发性十二指肠癌中33例位于十二指肠的降段,病理类型以腺癌最多见.临床表现以黄疸、腹痛或上腹不适、消化道梗阻及消化道出血为主,其中有3例并发胆肠瘘.检查方法以内镜结合病理检查再配合胃肠钡餐造影为主.外科手术是本病的主要治疗手段.结论:原发性十二指肠癌的预后差,早期诊断的关键是提高对本病的认识,对可疑患者及时做相应检查可提高诊断率.

Clinical Analysis of 43 Cases of the Primary Duodenal Carcinoma

Objective: To study the clinical manifestation, diagnostic methods and treatment of primary duodenal carcinoma, in order to provide reliable message for early diagnosis and treatment.Method: The records of 43 patients of primary duodenal carcinoma were retrospectively/analysed.Result: In 43 primary duodenal carcinomas, 33 located in the down section of the duodenum, the adenocarcinoma was more common in all pathologic types. The prominent clinical manifestations were jaundice, abdomen pains or epigastria discomfort, obstruction and hemorrhage of digestive tract, 3 patients were complicated by duodenocholangio fistulas.The main diagnostic procedures were endoscopic, upper GI barium meal, combined with pathologic diagnosis.Surgery was the main method of treatment for this carcinoma.Conclusion: the prognosis of the primary duodenal carcinoma was very poor, the understanding of duodenal carcinoma is the key factor for early diagnosis.The appropriate examinations are neeessiry for suspected patients, and it will increase the rate of early diagnosis.