| 骨质疏松性骨折经皮椎体后凸成形术后应用唑来膦酸的疗效分析 |
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| 引用本文： | 袁 亮,李正维,李靖年. 骨质疏松性骨折经皮椎体后凸成形术后应用唑来膦酸的疗效分析[J]. 大连医科大学学报, 2016, 38(1): 56-59. DOI: 10.11724/jdmu.2016.01.14 |
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| 作者姓名： | 袁 亮 李正维 李靖年 |
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| 作者单位： | 大连医科大学附属第二医院脊柱科,辽宁大连,116027 |
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| 摘 要： | 目的 探讨骨质疏松性骨折经皮椎体后凸成形术后应用唑来膦酸的临床疗效.方法 将82例骨质疏松性椎体压缩性骨折患者分为两组,分别为经皮椎体后凸成形术(PKP)组和PKP+唑来膦酸组,唑来膦酸治疗后1周及12个月对两组进行随访,并根据疼痛视觉模拟评分(VAS)、骨密度对治疗效果进行评价.结果 唑来膦酸治疗后1周,PKP+唑来膦酸组VAS评分(3.35 ±0.81)与PKP组(3.28±0.78)比较,差异无显著性意义(P＞0.05);治疗后12个月,PKP+唑来膦酸组VAS评分明显低于PKP组(P＜0.05).PKP组治疗后股骨近端骨密度(BMD)值与治疗前比较差异无显著性意义(P＞0.05),PKP+唑来膦酸组治疗后BMD较治疗前明显提高(P＜0.05);PKP+唑来膦酸组治疗后BMD与PKP组比较明显增高,差异有显著性意义(P＜0.05).结论 骨质疏松性骨折经皮椎体后凸成形术后应用唑来膦酸能明显降低腰背部疼痛,提高骨密度,并能遏制骨质疏松症的进一步发展.
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| 关 键 词： | 唑来膦酸 经皮椎体成形术 骨质疏松性骨折 |
| 收稿时间： | 2015-06-13 |
Efficacy analysis of zoledronic acid after percutaneous kyphoplasty for osteoporotic vertebral compression fractures |
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| YUAN Liang,LI Zheng-wei and LI Jing-nian. Efficacy analysis of zoledronic acid after percutaneous kyphoplasty for osteoporotic vertebral compression fractures[J]. Journal of Dalian Medical University, 2016, 38(1): 56-59. DOI: 10.11724/jdmu.2016.01.14 |
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| Authors: | YUAN Liang LI Zheng-wei LI Jing-nian |
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| Affiliation: | Department of Orthopedics, the Second Affiliated Hospital of Dalian Medical University, Dalian 116027,China,Department of Orthopedics, the Second Affiliated Hospital of Dalian Medical University, Dalian 116027,China and Department of Orthopedics, the Second Affiliated Hospital of Dalian Medical University, Dalian 116027,China |
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| Abstract: | |
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| Keywords: | zoledronic acid percutaneous kyphoplasty osteoporotic vertebral fractures |
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