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糖尿病脑病患者认知功能障碍的神经电生理学研究
引用本文:刘会锋,商淑梅,张树全,徐艳,苑杰,张熙泉. 糖尿病脑病患者认知功能障碍的神经电生理学研究[J]. 中国健康心理学杂志, 2011, 19(5): 542-543
作者姓名:刘会锋  商淑梅  张树全  徐艳  苑杰  张熙泉
作者单位:1. 中国.河北省滦县人民医院神经内科,063700
2. 河北省滦县人民医院神经电生理室
3. 河北联合大学
基金项目:河北省卫生厅医学科研重点课题项目
摘    要:目的 研究糖尿病脑病患者事件相关电位(ERP)的特征及早期评定患者有无认知功能障碍及严重程度的临床价值.方法 对39例糖尿病脑痛(DM&ICVD)患者、32例缺血性脑血管病(ICVD)患者及24例正常人进行事件相关电位检查及简易智能量表(MMSE)检测,将两组检测结果与正常对照组比较.结果 DM&ICVD组、ICVD组...

关 键 词:糖尿病脑病  简易智能量表  事件相关电位

Study on Event-related Potential in Cognitive Impairment Patients with Diabetes Encephalopathy
Affiliation:Liu Huifeng,Shang Shumei,Zhang Shuquan,et al.Neurology Department of Luanxian People's Hospital,Luanxian 063700,P.R.China
Abstract:Objective To investigate the characteristic of event-related potential(ERP) in patients with diabetes encephalopathy(DE).Methods A total of 39 patients with diabetes encephalopathy and 32 patients with ischemic cerebrovascular disease(ICVD) and 24 normal subjects were tested by event-related potentials(P300) and mini-mental state examination(MMSE),and the results were analyzed statistically.Results The latencies of P300 in the DMICVD group were significantly longer than those in normal subjects group respectively(P0.01).Significant difference in the MMSE scores was found between the DMICVD group and normal control group(P0.01).The prolongation of P300 latency in DMICVD group were related to the score of MMSE(r=-0.83,P0.01).Conclusion P300 can be a sensitive index in early diagnosis of cognitive impairment in patients with diabetes encephalopathy.
Keywords:Diabetes encephalopathy  Mini mental state examination  Event-related potential
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