| 肺癌放疗中活动靶区常规CT定位和PET/CT定位的模体研究比较 |
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| 引用本文： | 李承军,徐利明. 肺癌放疗中活动靶区常规CT定位和PET/CT定位的模体研究比较[J]. 中国医学物理学杂志, 2011, 28(4): 2743-2749. DOI: 10.3969/j.issn.1005-202X.2011.04.011 |
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| 作者姓名： | 李承军 徐利明 |
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| 作者单位： | 武汉大学人民医院放疗科,湖北武汉,430060 |
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| 摘 要： | 目的:肺癌靶区运动是影响放射治疗效果的重要因素之一,目前有很多方法试图解决这一问题,如4D-CT,呼吸门控,慢CT,等,但各有缺陷,都不理想。本文使用模体研究常规CT定位和PET/CT定位并比较。材料和方法:将不同形状CT模体/灌注F18-FDG模体,固定于呼吸运动平台上,使用Simens Biograph64同机PET-CT不同条件扫描(64排CT和39环PET),瓦里安Eclipse治疗计划系统三维重建,勾画并比较体积差异。结果:快速CT扫描运动模体,最大丢失体积达-50.8%(36.2 cm3);PET图像同物体运动轨迹体积比较最大差异-16.3%,且没有出现变形现象。PET图像所有体积小于真实运动轨迹体积,这同显示条件有关系。结论:快速CT只能随机捕捉运动物体部分体积并存在变形情况,不适合应用于活动肿瘤(肺癌)放射治疗计划定位;PET-CT能够较稳定地反映运动物体运动轨迹,且没有图像变形,能较好代表内靶区,并且操作相对简单,病人容易耐受。
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| 关 键 词： | 放射治疗 内靶区PET-CT 靶区运动 |
A Phantom Study for Lung Cancer Internal Target Volume (ITV) Decision by Employing PET-CT Image |
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| LI Cheng-jun,XU Li-ming. A Phantom Study for Lung Cancer Internal Target Volume (ITV) Decision by Employing PET-CT Image[J]. Chinese Journal of Medical Physics, 2011, 28(4): 2743-2749. DOI: 10.3969/j.issn.1005-202X.2011.04.011 |
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| Authors: | LI Cheng-jun XU Li-ming |
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| Affiliation: | LI Cheng-jun,XU Li-ming(Department of Radiation oncology,People's Hospital of Wuhan University,Wuhan Hubei 430060,China) |
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| Abstract: | Objective: The moving lung cancer is difficult to define in the process of treatment planning.At present there are many methods to be employed to solve this problem,such as 4D-CT,gating and slow CT,but they are far more perfect.In this study,we try to investigate whether PET-CT can predict the internal target volume by imaging a moving phantom.Methods and Materials: The CT phantom and a ball filled with F18-FDG were immobilized on the Respiratory gating platform respectively and imaged by the Simens Biograp... |
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| Keywords: | radiotherapy ITV PET-CT moving target |
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