肥胖儿童脂代谢变化及其与身体指标的相关性研究

检测１０２例６～１５岁单纯肥胖症儿童及７７例同龄健康儿童的血脂及身体指标，以探讨肥胖儿童脂质代谢的变化及其与Ｒｏｈｌｅｒ指数、体质量（体重）指数（ＢＭＩ）的相关关系。发现肥胖儿童较健康儿童胆固醇（ＴＣ）、甘油三酯（ＴＧ）、极低密度脂蛋白胆固醇（ＶＬＤＬ Ｃ）及低密度脂蛋白胆固醇（ＬＤＬ Ｃ）、动脉硬化指数（ＡＩ）明显增高（Ｐ＜０．００１、０．０１及０．０５），高密度脂蛋白胆固醇（ＨＤＬ Ｃ）及其与ＴＣ之比值明显降低（Ｐ＜０．０５及０．００１）。多元逐步回归证实，在排除众多血脂因素之后，肥胖儿童ＴＧ分别与Ｒｏｈｌｅｒ指数及ＢＭＩ呈明显正相关，是影响Ｒｏｈｌｅｒ指数与ＢＭＩ的独立因素。

A Study on Relationship between Body Status and Metabolism of Lipids in Simple Obese Children

For investigation of the correlation between body status and metabolism of lipids, the lipid levels and body mass index, Rohler index were examined in 102 simple obese children aged 6 to 15 years and 77 age matched healthy children. It was found that total cholesterol, triglyceride, very low density lipoprotein, low density lipoprotein cholesterol and atherosclerosis index were significantly increased( P <0.05, and P <0.01), while the level of high density lipoprotein was decreased( P <0.05), in obese children than in healthy children. Stepwise multivaritate regression analysis disclosed that triglyceride alone and jointly positively correlated with body mass index and Rohler index except multiple markers of lipids.