从检测血中FT3、FT4、T、E2及皮质醇等指标探讨寒证热证的本质

目的：探讨内分泌激素FT3、FT4、T、E2及皮质醇（cortisol,CO)水平与中医寒证热证的相关规律。方法：选实热、虚热、实寒、虚寒证患者202例及健康对照组50名，检测血中FT3、FT4、T、E2、CO指标。结果：（1）FT3、FT4数值热证高而寒证低，依次为虚热证组＞实热证组＞对照组＞实寒证组＞虚寒证组，提示热证基础代谢及氧消耗升高而寒证正相反。（2）CO值实证高而虚证低，依次为实寒证组＞实热证组＞对照组＞虚热证组＞虚寒证组，提示CO为形成虚实的因素之一而与寒热关系不显著。（3）性激素T热证高而寒证低；E2女性热证低而寒证高。提示T值高为形成热证的因素之一，E2值高为形成女性寒证的因素之一。结论：内分泌激素水平的高低是形成寒证热证的主要病理生理基础之一。

Determining Blood Parameters FT3, FT4, T, E2 and Cortisol to Expl ore Nature of Cold Syndrome and Heat Syndrome

To explore the relationship between the level s of free triiodothyronine (FT 3), free thyroxine (FT 4), cortisol (CO), testosterone (T), serum estradiol (E 2) and Cold Syndrome and Heat Syndrome in traditional Chinese medicine. Methods: The blood levels of FT 3, FT 4, T, E 2, CO in gro u ps of sthenic Heat (SH), sthenic Cold (SC), asthenic Heat (AH) and asthenic Cold (AC) and the healthy control group were measured. The number of cases in each g roup was 50. Results: (1) FT 3 and FT 4 were higher in Heat Syndrome than that in Cold Syndrome in the order of AH>SH>control>SC>AC, it revealed that the basal metabolic rate and oxygen consumption in Heat Syndrome were incr eased, while it in Cold Syndrome, it declined. (2) CO was higher in SH, SC than that in AH and AC, the order was SC>SH>control>AH>AC, it revealed that CO wa s one of the factors correlated to asthenic and sthenic syndrome, but not releve nt to Heat Syndrome and Cold Syndrome. (3) T was higher in Heat Syndrome than th at in Cold Syndrome, but E 2 showed the opposite, suggesting that T was one of the factors for forming Heat Syndrome, and E 2 for Cold Syndrome. Conclusion: The levels of FT 3, FT 4, T, E 2 are basis of p athophysiology related with forming HS and CS.