足剂量雾化吸入布地奈德对急性喘息性支气管炎患儿临床症状的影响

目的探讨足剂量雾化吸入布地奈德对急性喘息性支气管炎患儿临床症状的影响。方法选择2017年10月至2019年3月我院收治的60例急性喘息性支气管炎患儿,随机分为观察组和对照组各30例。两组均进行常规对症治疗,基于此,对照组雾化吸入低剂量布地奈德,观察组雾化吸入足剂量布地奈德。比较两组患儿治疗后临床症状改善情况、肺功能指标及不良反应情况。结果治疗后,观察组的咳嗽缓解时间、咳嗽消失时间、肺部哮鸣音消失时间、气促缓解时间均短于对照组(P<0.05);两组的FVC、FEV1及PEF均上升,且观察组的FVC、FEV1及PEF高于对照组(P均<0.05)。两组的不良反应发生率比较无统计学差异(P>0.05)。结论足剂量雾化吸入布地奈德治疗急性喘息性支气管炎的效果确切,可快速改善患儿的临床症状,增强其肺功能,且安全性高,值得推广应用。

Influence of Full-Dose Atomization Inhalation of Budesonide on Clinical Symptoms of Children with Acute Asthmatic Bronchitis

Objective To explore the influence of full-dose atomization inhalation of budesonide on clinical symptoms of children with acute asthmatic bronchitis.Methods 60 children with acute asthmatic bronchitis admitted to our hospital from October 2017 to March 2019 were selected and randomly divided into observation group and control group equally.Both groups were given routine symptomatic treatment.Based on this,the control group received low-dose atomization inhalation of budesonide,and the observation group was given full-dose atomization inhalation of budesonide.The improvement of clinical symptoms after treatment,lung function indicators and adverse reactions were compared between two groups.Results After treatment,the relief time of cough,disappearance time of cough,disappearance time of lung wheeze,and the relief time of anhelation in the observation group were shorter than those in the control group(P<0.05).The FVC,FEV,and PEF of both groups increased,and the FVC,FEV,and PEF of observation group were higher than those of control group(all P<0.05).No statistical difference was found in the incidence of adverse reactions between the two groups(P>0.05).Conclusions Full-dose atomization inhalation of budesonide has exact effect in the treatment of acute asthmatic bronchitis,can rapidly improve the clinical symptoms of children and enhance the lung function,with high safety,which is worthy of promotion and application.