胃癌高发区高危人群普查检出胃癌的特点分析

探讨胃癌高发区高危人群普查检出的胃癌的特点。方法采用两轮筛选法，第一轮选择３５岁以上并有胃病史或胃癌家族史者，检测血清胃蛋白酶含量并进行胃双重对经检查，第二轮进行胃镜检查及病理活检。结论胃癌高发区高危人群中胃癌检出率较高，而且早期胃癌较多，对此人群有针对性地，有计划地开展一、二级预防具有重要意义。

Characteristics of gastric cancer in screening

Objective The significance of gastric cancer detected in screening among high risk population from high risk area in northern China was explored. Methods The method of two round screening was adopted. Subjects submitted to the first round were chosen from those aged over 35 years with history of gastric disorder or family history of gastric cancer, receiving blood test for pepsinogen and double contrasted X-ray study of stomach. Gastroscopy and biopsies were reserved for the second round. Results 3033 individuals had the first round tests, from which 1781 cases were screened to have second round exams. 32 gastric cancers were found, of which 18 being the early (56.25%) and 14 (43.75%) the advanced cancers. Macroscopically mixed type of early cancer (n=9, including 5 one-point cancers) and various types of the advanced ones (n=13) were often seen. Microscopically tubular adenocarcinomas composed the major part. Conclusion In high risk population from high risk area the detection rate of gastric cancer increased evidently with more early cancers, It is mandatory to take particular and programed preventive measures against the cancer.