广东省ZH市一起新型冠状病毒肺炎家庭聚集性疫情流行病学调查分析

目的 调查并分析广东省ZH市一起新型冠状病毒肺炎（COVID-19）家庭聚集性疫情,为COVID-19的科学防控提供更多证据。方法 采用现场流行病学方法调查病例及密切接触者,采用实时荧光RT-PCR技术对咽拭子等样本进行新型冠状病毒核酸检测。结果 该家庭首发病例于1月28日发病后,该家庭相继发生6例确诊病例,疫情波及4个小家庭,共7例病例。病例以呼吸系统症状为主,其中1例危重型、1例重型、5例普通型病例。7例病例年龄中位数为63岁（36~67岁）;男性3名,女性4名。病例潜伏期中位数为8 d（7~14 d）。结论 COVID-19早期传播易出现家庭聚集性,疫情初期采取单人单间的集中隔离可以有效切断家庭内传播途径。

Epidemiological investigation of a family clustering of COVID-19 in ZH City,Guangdong

Objective To investigate and analyze a family clustering of COVID-19 in ZH City,Guangdong Province,with a view to providing more evidence for the scientific prevention and control of COVID-19.Methods Field epidemiological method was used to survey the cases and related close contacts.Real time-PCR technique was used to detect SARS-CoV-2 nucleic acid in throat swab samples collected from the respondents.Results After the onset of the first case on January 28,6 confirmed cases had occurred in this family,and the epidemic had affected 4 small families with a total of 7 cases.The main symptoms were respiratory symptoms,including 1 critical case,1 severe case,and 5 common cases.The median age of 7 cases was 63 years(36-67 years);3 were males and 4 were females.The median exposure-onset interval was 8 d(7-14 d).Conclusion The early transmission of COVID-19 is prone to family aggregation,and the centralized isolation of single people and single room in the early stage of the epidemic can effectively cut off the transmission route within the family.