胃癌的免疫治疗

胃癌免疫治疗主要包括细胞因子疗法、单克隆抗体疗法、肿瘤疫苗等方法.基因免疫疗法是当前研究的热点,研究发现,Gbl-b基因在调节机体抗肿瘤免疫方面发挥着重要作用,Cbl-b蛋白与胃癌淋巴转移密切相关.通过沉默T淋巴细胞Cbl-b基因从而增强机体的抗肿瘤免疫有望在晚期胃癌治疗上取得良好的效果.

Immunotherapy of gastric cancer

The primary immunotherapy for gastric cancer includes cytokine therapy,monoclonal antibody therapy, and cancer vaccines. A lot of researches are being conducted to study gene immunotherapy. It has found that Cbl-b gene plays an important role in regulating anti-tumor immunity and Cbl-b protein is involved in the lymph node metastasis of gastric cancer. Silencing Cbl-b gene in T lymphocytes can enhance anti-tumor immunity,therefore may become an effective treatment for patients with advanced gastric cancer.