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The use of warfarin as thromboprophylaxis for lower limb arthroplasty
Authors:Dunbar Mark R  Upadhyay Piyush K  Karthikeyan Shanmugam
Affiliation:Academic Department of Orthopaedics, Warwick Medical School, Clinical Sciences Research Institute, University Hospital, Coventry, UK. mdunbar@btinternet.com
Abstract:

INTRODUCTION

Most orthopaedic surgeons in the UK use some form of prophylaxis against venous thromboembolic events. Warfarin has been recommended as one of the preferred methods to use. The period of in-hospital postoperative rehabilitation has reduced significantly since lower limb arthroplasty was introduced. We sought to identify and quantify any delay in discharge associated in using warfarin as chemical prophylaxis.

PATIENTS AND METHODS

During a 12-week period, all patients undergoing a lower limb arthroplasty procedure were identified and any delay in discharge related to their warfarin prophylaxis was recorded.

RESULTS

Of the 25 arthroplasties performed in this time period, 17 (68%) were subject to a delay. The total delay in discharge was 39 days. When the standard warfarin dosing protocol was followed, 33% of patients were still delayed. When the protocol was not followed, only 23% were delayed. The majority of deviations from the protocol led to a shorter hospital stay.

DISCUSSION

Patients using warfarin prophylaxis generate an additional cost of £417 related to bed occupancy. There is considerable scope for significantly reducing this cost by moving the early postoperative anticoagulation monitoring into the community. Delayed discharge is an important consideration in the economic issues that surround the choice of thromboprophylaxis.
Keywords:Warfarin   Arthroplasty   Medical audit
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