偏头痛患者血液微循环特征探讨

目的 探讨偏头痛患者的血液微循环特征。方法 观察50例偏头痛患者的红细胞流变性、血液流变性及甲襞微循环变化，并与50例健康人作对照。结果 偏头痛患者红细胞流变性异常，表现为红细胞聚集性增高、红细胞变形性降低；血液黏度增高，呈高黏高凝状态；甲襞微循环异常，主要表现为流态异常、襻顶瘀血、异型管襻数量增多、红细胞聚集、管襻长度缩短、开放管襻数量减少、襻周渗出等。结论 红细胞流变性异常、血液呈高黏高凝状态、微循环障碍是偏头痛患者的血液微循环特征。偏头痛患者血液微循环的异常改变可能是偏头痛的病因之一。

Research on Migraine''''s Properties of Blood Circulation

Objective To explore the properties of microcirculation of migraine. Methods By measuring erythrocyte rheology, hemorheology and nailfold microcirculation of 50 migraine patients contrasted to 50 healthy persons.Results Migraine patients viscosity of whole blood, viscosity of plasma and aggregation of RBC increase,while deformability of RBC decrease. The nailfold microcirculation is out of order. Blood flow is abnormal. The number of nailfold microcirculation capillary loops decrease, while deviant capillary loops increase.Capillary loops are shortened. Conclusions The abnormal changes of erythrocyte rheology, hemorheology and nailfold microcirculation are the migraine's properties of microcirculation. It may be one of the reasons of migraine.