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| 晚期妊娠妇女尿脱氧吡啶啉与尿肌酐比值的测定及临床意义 | |
| 引用本文： | 杨立伟,毛威,王亮,应奇峰,周永列,程素兰.晚期妊娠妇女尿脱氧吡啶啉与尿肌酐比值的测定及临床意义[J].中国生育健康杂志,2001,12(3):107-109. |
| 作者姓名： | 杨立伟 毛威 王亮 应奇峰 周永列 程素兰 |
| 作者单位： | 1. 310014,杭州,浙江省人民医院妇产科 2. 浙江中医学院西内科教研室 3. 310014,杭州,浙江省人民医院中心实验室 |
| 摘 要： | 目的了解正常晚期妊娠(晚妊)妇女尿脱氧吡啶啉(deoxypyridinoline,DPD)和尿肌酐(creatinine,Cr)比值(DPD/Cr)及其与骨钙代谢关系.方法测定80例正常晚妊妇女(1ate normal pregnant women,LPW)及22例正常非孕妇女(normal nonpregnant women,NPW)尿DPD、尿Cr和血钙离子浓度(serum calcium,SCa),并计算DPD/Cr.尿DPD浓度用化学发光法测定.结果晚妊妇女尿DPD/Cr比值明显增高,与正常非孕妇女比较,差异有显著性(P＜0.001),晚妊妇女SCa与正常非孕妇女比较略有下降,但差异无显著性(P＞0.05).结论尿DPD/Cr较SCa能更准确、灵敏、特异地反映体内缺钙状况,是孕期保健中值得推荐的骨钙代谢监测指标. |
| 关 键 词： | 尿脱氧吡啶啉 尿肌酐 血钙 晚期妊娠妇女 |
| 修稿时间： | 2001年2月22日 |
Measurement and clinical significance of the ratio of urine deoxypyridinoline and urine creatinine in late normal pregnant women |
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| YANG Liwei,MAO Wei,WANG Liang,et al..Measurement and clinical significance of the ratio of urine deoxypyridinoline and urine creatinine in late normal pregnant women[J].Chinese JOurnal of Reproductive Health,2001,12(3):107-109. | |
| Authors: | YANG Liwei MAO Wei WANG Liang |
| Institution: | YANG Liwei,MAO Wei,WANG Liang,et al. Gynaecologic and Obstetrical Department,Zhejiang Provincial People's Hospital,hangzhou 310014,China |
| Abstract: | Objective To investigate the ratio of urine deoxypyridinoline (DPD) and uring creatinine (Cr) (DPD/Cr) in late normal pregnant women (LPW) and the relationship between DPD/Cr and bone calcium metabolism. Methods The parameters, DPD/Cr and serum calcium comcentration (SCa) were measurde in 80 LPW and 20 normal non-pregnant wome (NPW). DPD was detected by chemoluminescent immunoassay (CLI-A). Results Urine DPD/Cr in LPW group was significantly higher than that in NPW group (P<0. 001) but SCa level did not show significant difference between these two groups (P>0. 05), although SCa level lowered slightly in LPW group. Conclusion Urine DPD/Cr could reflect lack of calcium within body more sensitively, accurately and specifically than SCa, and may be used as a valuable parameter to detect bone calcium metabolism during pregnancy. |
| Keywords: | Urine deoxypyridinoline Urine creatinine Serum calcium concentration Late normal pregnant women |
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