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| Inhibition of the Specific ^3H—DL—Glu Binding in the Hippocampus of Rat Brain by Lead | |
| 摘 要： | INTRODUCTIONLead(Pb' )poisoningremainsasignificantpublichealthproblemtochildrenbecauseofitsneurotoxicity.Inhumans,exposureleadingtobloodPb2 levelsaslow'as1OUg/1oOmlhasbeenshowntocausesignificantimpairmentofcognitivefunc-tions'andsignificantdelaysinbehavioraldevelopment(Bellingeretal.,1989;DavisandSvendsgaard,1987;NeedlemanandGatsonis,199O).Similarly,animalstudieshaveindicatedthatexposuretolowlevelsofPb2 duringdevelopmentproducescogni-tivedysfunctioninthepresenceofbloodPb2 valuesof15-… |
| 关 键 词： | 大鼠脑 海马 铅毒 特异性^3H－DL－谷氨酸结合 抑制作用 学习 记忆 |
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