| 温法干预治疗慢性乙型重型肝炎阳黄湿热内蕴(湿重于热)证的临床疗效与安全性研究 |
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| 引用本文： | 孙克伟,龚磊,陈斌,黄裕红,伍玉南,阳航,朱文芳,张涛,彭建平,陈兰玲. 温法干预治疗慢性乙型重型肝炎阳黄湿热内蕴(湿重于热)证的临床疗效与安全性研究[J]. 中西医结合肝病杂志, 2010, 20(3): 135-137. DOI: 10.3969/j.issn.1005-0264.2010.03.003 |
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| 作者姓名： | 孙克伟 龚磊 陈斌 黄裕红 伍玉南 阳航 朱文芳 张涛 彭建平 陈兰玲 |
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| 作者单位： | 湖南中医药大学第一附属医院传染病科、湖南省中医药管理局重型肝炎证治研究室,湖南,长沙,410007 |
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| 基金项目： | 国家科技重大专项"十一五"课题"慢性重型肝炎证候规律及中西医结合治疗方案研究" |
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| 摘 要： | 目的:比较清热利湿法加与不加温阳健脾药物治疗慢性重型肝炎(阳黄、湿重于热型)的疗效。方法:采用随机、对照方法,将60例中医辨证为湿重于热的慢性重型肝炎分为两组,分别给予甘露消毒丹(非温法干预组)和甘露消毒丹加附片、白术(温法干预组)治疗。结果:治疗4周,温法干预组和非温法干预组有效率分别为93.1%和72.41%。两组患者的TBil均有明显下降,温法干预组的下降幅度较非温法干预组明显,治疗前后差值分别为(228.62±89.18)和(176.70±97.94)μmol/L,两组比较,P0.05。PTA水平都有不同程度的升高,温法干预组PTA水平上升的幅度大于非温法干预组,上升幅度均数比较,P0.05。未发现温法干预组患者出现感染、出血及黄疸加重等不良反应。结论:清热利湿法加用附片、白术可提高慢性重型肝炎湿重于热证的疗效,且安全性良好。
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| 关 键 词： | 重型肝炎,乙型,慢性 甘露消毒丹/治疗应用 附片/治疗应用 白术/治疗应用 |
Efficacy and safety of Ganluxiaodudan (TCM decoction) treatment in patients with chronic severe hepatitis B |
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| SUN KE-WEI,GONG LEI,CHEN BIN,et al.. Efficacy and safety of Ganluxiaodudan (TCM decoction) treatment in patients with chronic severe hepatitis B[J]. Chinese Journal of Integrated Traditonal and Western Medicine on Liver Diseases, 2010, 20(3): 135-137. DOI: 10.3969/j.issn.1005-0264.2010.03.003 |
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| Authors: | SUN KE-WEI GONG LEI CHEN BIN et al. |
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| Affiliation: | SUN KE-WEI,GONG LEI,CHEN BIN,et al.The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine(Changsha Hunan,410007)China |
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| Abstract: | Objective:To observe the efficacy and safety of TCM decoction Ganluxiaodudan(GD) and Ganluxiaodudan plus Monkshood and Atractylodes(GDp) treatment in patients with chronic severe hepatitis B(CSHB).Methods:Sixty patients with CSHB were randomly divided into two groups,one received GD,another GDp,for 4 weeks.Level of serum bilirubin,PTA and adverse events were observed.Results:The efficient was 93.1%(27/29),72.41%(21/29) in group GD and GDp respectively.Level of serum bilirubin was significantly lower in both... |
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| Keywords: | chronic severe hepatitis B Ganluxiaodudan/therapeutic use monkshood/therapeutic use atractylodes/therapeutic use |
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