| Effect of 1,25—Dihydroxyvitamin D3on Gastric Carcinogenesis Induced by N—Methyl—N—nitro—N—nitrosoguanidine in Rats |
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| 引用本文： | GAOGUO－LIN YANGYUAN.Effect of 1,25—Dihydroxyvitamin D3on Gastric Carcinogenesis Induced by N—Methyl—N—nitro—N—nitrosoguanidine in Rats[J].生物医学与环境科学,1998,11(2):147-155. |
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| 作者姓名： | GAOGUO－LIN YANGYUAN |
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| 摘 要： | INTRODUCTlONThehormonallyactiveformofvitaminD3(1,25(OH),D3)hasawellrecognizedroleinregulatingcalciumabsorptionandmineralmetabolism.Inthepastloyears,therehasbeenincreasinginterestintheroleof1,25(OH),D,inregulatingprolifera-tionanddifferentiatlonoftumorcellsincancerssuchasleukemia,breastcarc1noma,coloncarcinomaandmelanoma.(Kogaetal.,1988;Mangelsdorfetal.,1984;Shabahangetal.,1994;Reicheletal.,1989).Theantiproliferatingactivityof1,25(OH)zD3wasalsostudiedinvivo(Eismanetal.,1987;Honmaetal.…
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| 关 键 词： | 1 25（OH2）D3 MNNG 胃癌 诱导 动物实验 PCNA |
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