多元回归分光光度法测定复方乙酰水杨酸片中的非那西丁和咖啡因的含量

目的：观察灯盏花素治疗脑梗塞的疗效。方法：１８０例脑梗塞病人，其中男９５例，女８５例。年龄（６２±７３）ａ。采用灯盏花素注射液１０～２０ｍｌ加入生理盐水５００ｍｌ，静脉滴注，每天１次，１４ｄ为１疗程。隔２～３ｄ进行第２疗程。对照组１１０例，男６８例，女４２例。年龄（６１８±６８）ａ。采用低分子右旋糖酐５００ｍｌ静滴，方法、疗程同治疗组。结果：灯盏花素组总有效率８５％，显效率７３％。右旋糖酐组总有效率７０％，显效率３５％，经Ｒｉｄｉｔ分析：Ｐ＜００５。同时还显示灯盏花素对血脂、血液流变学均有显著改善（Ｐ＜００５）。该药不良反应少。结论：灯盏花素是治疗脑梗塞的良好药物。

Determination of phenacetin and caffeine in compound acetylsalicylic acid tablets by multiple regression spectrophotometry

OBJECTIVE To determine phenacetin and caffeine in compound acetylsalicylic acid tablets. METHODS Multiple regression spectrophotometry was adopted as follow:The sample is dissolved in ethanol,add solution of 02mol/L NaOH to hydrolysis acetylsalicylic acid,the components are determined in phosphate salt buffet (pH 6.5). RESULTS The average recoveries for phenacetin and caffeine were 99.8% and 99.9%,with RSD 0.72% and 0.52%,respectively. CONCLUSION Accuracy of the method was compared with official quantitative analysis and no significant difference was found.