Liposome-bound cyclosporine: Retinal toxicity after intravitreal injection |
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Authors: | Abdulrahman A. Alghadyan Gholam A. Peyman MD Bahram Khoobehi Kwan-Rong Liu |
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Affiliation: | (1) LSU Eye Center, Louisiana State University Medical Center School of Medicine, New Orleans, Louisiana, USA;(2) LSU Eye Center, 2020 Gravier St., Suite B, 70112 New Orleans, LA, USA |
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Abstract: | The retinal toxicity of intraocular liposome-bound cyclosporine was studied in albino rabbits by means of electrophysiology and histopathology. During a followup period of one month, no histopathological or electroretinographic changes were noted using concentrations of 100, 200 and 500 micrograms injected intravitreally. |
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Keywords: | cyclosporine liposomes rabbits retina vitreous |
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