临床标本分离病原菌种类及耐药分析

目的 对本院2005～2006年临床分离的924株病原菌种进行药敏试验和耐药分析.方法 革兰阳性球菌及阴性杆菌采用MicroScan细菌鉴定药敏检测系统板进行细菌鉴定和药敏试验.结果 革兰阴性杆菌占优势(67.86%),主要为大肠埃希菌(14.07%)、铜绿假单胞菌(13.53%)、肺炎克雷伯菌(11.04%)、表皮葡萄球菌(6.79%)、金黄色葡萄球菌(4.52%).各种常见病原菌对抗生素存在不同程度的耐药.结论 阳性球菌对万古霉素100%敏感,对青霉素100%耐药,治疗阴性杆菌感染首选亚胺硫霉素(76.1%敏感),其次是丁胺卡那霉素(71.7%敏感).建议临床医生根据实验室结果合理使用抗生素.

Pathogens isolated from clinical samples and their drug resistances

Objective To analyse the drug resistance for 924 strains of pathogens isolated from clinical samples in Xinhai Hospital during 2005 to 2006.Methods MicroScan bacterial identification and drug susceptibility testing system plate were used to identify and perform the susceptibility test for Gram positive coccus and Gram negative bacilli.Results Gram negative bacilli were the superiority bacteria(67.86%),mainly Escherichia coli(14.07%),Pseudomonas aeruginosa(13.53%),Klebsiella pneumoniae(11.04%),Staphylococcus epidermidis(6.79%)Staphylococcus aureus(4.52%).Each kind of these common pathogens existed antibiotic resistance to varying degree.Conclusion Staphylococcus is sensitive(100%)to Vancomycin and resistant(100%)to penicillin.To Gram negative bacillus,the first choice is imipenem(76.1% sensitive),the next is amikacin(71.7% sensitive).It is suggested that the clinical doctors should use antibiotics rationally according to the laboratory results.