肝硬化患者胆碱酯酶与总胆汁酸及凝血功能检测的意义

目的 探讨肝硬化患者胆碱酯酶(CHE)、总胆汁酸(TBA)和凝血功能的变化及其临床意义.方法 选取肝炎后肝硬化患者56例,健康对照30例,均检测血清CHE、TBA和血浆凝血酶原时间(PT),活化部分凝血活酶时间(APTT)、纤维蛋白原(Fbg)含量以及凝血酶时间(TT).结果 肝硬化患者CHE、TBA、PT、APTT、Fbg和TT与对照组比较差异均有统计学意义.结论 联合测定CHE、TBA和凝血功能对肝硬化患者的病情判断有重要的临床意义.

Detemination of cholinesterase, total bile acid and blood coagulation function in liver cirrhosis and its significance

Objective To investigate clinical significance of measurement of cholinesterase, total bile acid and blood coagulation function in liver cirrhosis.Methods Serum cholinesterase (CHE), total bile acid (TBA), plasma prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen (Fbg) and thrombin time (TT) were measured in patients with liver cirrhosis (n=56) and healthy control people (n=30).Results There was significant difference of serum CHE, TBA, APTT and Fbg between liver cirrhosis group and healthy control group(P<0.01).Conclusion Combined detection of CHE, TBA and blood coagulation function in liver cirrhosis is of important clinical significance in evaluating state of liver cirrhosis.