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男性老年骨质疏松症患者血清IL-6、BGP和T含量变化及临床意义
引用本文:郑志良 吴家明 何浩明. 男性老年骨质疏松症患者血清IL-6、BGP和T含量变化及临床意义[J]. 放射免疫学杂志, 2005, 18(5): 339-341
作者姓名:郑志良 吴家明 何浩明
作者单位:江苏省溧阳市人民医院 (213300)(郑志良,吴家明),江苏省连云港市第一人民医院 (222002)(何浩明)
摘    要:目的:探讨老年骨质疏松症患者血清白细胞介素-6(IL-6)、骨钙素(BGP)和睾酮(T)含量的变化及临床意义。方法:应用放射免疫分析对46例老年骨质疏松症患者进行了血清IL-6、BGP和T水平测定,并与35名正常健康人作比较。结果:老年骨质疏松症患者血清IL-6水平明显高于正常健康人(P<0.01),而BGP、T水平明显低于正常人(P<0.01)。结论:测定老年骨质疏松症患者血清中IL-6、BGP和T水平为临床诊断治疗提供了一个有价值的数据。

关 键 词:老年骨质疏松  白细胞介素-6  骨钙素  睾酮
收稿时间:2005-05-14
修稿时间:2005-05-14

Clinical Significance of the Changes of Serum Contents of IL-6,BGP and Testosterone in Aged Male Patients with Osteoporosis
Zeng Zhiliang, Wu Jiaming, He Haoming. Clinical Significance of the Changes of Serum Contents of IL-6,BGP and Testosterone in Aged Male Patients with Osteoporosis[J]. Journal of Radioimmanology, 2005, 18(5): 339-341
Authors:Zeng Zhiliang   Wu Jiaming   He Haoming
Abstract:Objective To explore the clinical significance of changes of serum contents of IL-6,bone glaprotein (BGP) and testosterone (T) in aged male patients with osteoporosis. Methods Serum IL-6,BGP and T levels were determined with RIA in 46 aged male patients with osteoporosis and 35 controls. Results The serum levels of IL-6 were significantly higher but levels of BGP,T were significantly lower aged male patients with osteoporosis than those in controls (P<0.01). Conclusion Through measurement of serum IL-6,BGP and T levels in these patients, valuable data were obtained, which in turn would provide guidelines for diagnosis and treatment.
Keywords:aged osteoporosis   interleukin-6(IL-6)   bone glaprotein (BGP)   testosterone(T)
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