早产儿呼吸暂停治疗研究进展

新生儿呼吸暂停分为原发性呼吸暂停和继发性呼吸暂停，原发性呼吸暂停最主要原因为早产。早产儿呼吸暂停（ AOP）为目前新生儿重症监护中面临的主要问题之一。俯卧位、甲基黄嘌呤类药物和持续气道正压通气（ CPAP）是目前治疗AOP的主要有效方法，而经鼻间歇正压通气（ NIPPV）、湿化高流量鼻导管通气（ HHFNC）、触觉、嗅觉的刺激、吸入二氧化碳等治疗方式仍有待进一步临床研究。该文就AOP的治疗研究进展作一综述。

Advances in treatment for apnea of prematurity

Neonatal apnea is divided into primary apnea and secondary apnea .Premature is the main reason for primary apnea .Apnea of prematurity （ AOP） is one of the main clinical problems in the neonatal intensive care u-nit.Standard clinical management of AOP includes prone positioning , methylxanthine therapy and nasal continuous positive airway pressure（NCPAP）,other therapies, including nasal intermittent positive pressure ventilation （NIP-PV）,humidified high flow therapy via nasal cannula （HHFNC）,sensory stimulations, CO2 inhalation ect, require fur-ther study.This review focuses on the AOP therapies .