新生儿先天性梅毒30例临床分析

目的：探讨新生儿先天性梅毒的早期诊治与预后的关系。方法对该院2005～2012年收治的30例新生儿先天性梅毒的临床资料进行回顾性分析。结果新生儿梅毒的临床表现以皮疹、黄疸为主。梅毒血清学检查快速血浆反应素环状卡片试验和梅毒螺旋体血球凝集试验均阳性。选用青霉素静滴2～3周治疗，全部治愈。结论新生儿先天性梅毒早期使用青霉素静滴，疗效满意。常规开展孕期梅毒检测，早发现、早治疗，可明显降低先天性梅毒的发病率和病死率。

Clinical analysis of 30 cases of neonatal congenital syphilis

Objective To explore the association between the early diagnosis as well as treatment and the prognosis of neonatal congenital syphilis .Methods Thirty neonatal cases of congenital syphilis collected from 2005 to 2012 in our hospital were analyzed retrospectively .Results The main manifestations of neonatal congenital syphilis were skin lesions, jaundice, and positive laboratory examinations of rapid plasma reagin test and treponema pallidum hemagglutination test .All patients were cured with two to three weeks treatment with penicillin .Conclusion A satis-factory effectiveness would be attained with early treatment with intravenous penicillin for neonatal congenital syphilis . The morbidity and mortality of congenital syphilis could be greatly reduced with the routinely testing for syphilis in pregnant women for early diagnose and treatment .