右侧星状神经阻滞对大鼠体外循环微循环的影响

目的：研究右侧星状神经节阻滞（ SGB）对大鼠体外循环（ CPB）转流期间微循环变化的影响。方法选用20只SD大鼠随机分为体外循环组（C组）10只，右侧行星状神经节阻滞＋体外循环组（RC组）10只。两组转体循环后转流1 h。在转流前，定于动脉静脉置管成功后为T0；体外循环转流开始后30 min为T1；体外循环后1 h为T2。3个时间点观察两组大鼠的血压、心率、血气及乳酸含量，计算动静脉血氧分压差（ Pa-vO2）。结果两组大鼠乳酸、Pa-vO2和血压不同时间点差异有统计学意义（ P＜0.05）；两组心率、乳酸和Pa-vO2的组间和分组间有交互作用（P＜0.05）；两组心率和乳酸的组间差异有统计学意义（P＜0.05）。结论SGB能改善大鼠体外循环后的灌注，可提高机体的摄氧能力，改善机体的微循环。

The effects of right stellate ganglion block on rat microcirculation during extracorporeal circulation

Objective To observe the effects of right stellate ganglion block （SGB） on rat microcirculation nbsp;during extracorporeal circulation .Methods Twenty healthy SD rats were selected and randomly divided into two groups：control group（C group）and SGB group（RC group）.Both C group and RC group were processed by extracor-poreal circulation for 1 h.RC group received stellate ganglion block with bupivacaine before Undergoing cardiopulmo -nary bypass .The observation points included T 0：before extracorporeal circulation;T1： after 30 min of extracorporeal circulation;T2：after 1 h of extracorporeal circulation .The observation included blood pressure , heart rate,blood gas parameters difference of oxygen pressure between artery and vein （ Pa-vO2 ） and blood lactate .Results There were significant difference in lactate , Pa-vO2 and blood pressure at different time between two groups （ P〈0.05 ） .There was an interavtion effect in heart rate , lactate and Pa-vO2 between treatment and time（P〈0.05）.There were signifi-cant difference in the lactate and heart rate between two groups （ P〈0.05 ） .Conclusion Right stellate ganglion block can improve the tissue perfusion by ameliorating rat microcirculation during extracorporeal circulation .